Free radical scavenging potential of methanol extract of Ficus thonningii leave and liquid chromatography-mass spectrometer (LCMS) profiling

This study evaluated the in vitro and vivo free radical scavenging potentials of methanol extract Ficus thonningii leaf its liquid chromatography-mass spectrometer (LCMS) profiling. The qualitative phytochemical screening was carried out results show presence tannins, flavonoids, saponins glycoside triterpenes. Antioxidant activities were reducing power shows a value 0.53 ± 0.007 with significant (p < 0.05) difference compared to control Diphenylpicrylhydrazyl (DPPH) 59.0 significantly different control. However, two assays are concentration-dependent. analysis that lipid peroxidation, superoxide dismutase catalase have values 24.03± 8.04, 1.60± 0.03 0.003± 0.001 respectively. All when LCMS revealed some important metabolites; phenolic glycosides quassin, which potential molecules against radicals. Therefore, contains vital antioxidants could be used health management boost immune system or drug development.